7 Best Weight Loss Pills and Supplements That Work


hands with lot of supplements

HEY! DO NOT Buy Any Diet Pill until you read My REVIEW based on Real, High Quality, and Fully Researched Information! These Tips Helped Over 104,000 Readers of SkinnyWithFiber!

Weight loss pills are one of the most controversial topics in the entire fitness world (and for good reason). The concept of taking a capsule to boost the process of losing weight is one that must be analyzed on many fronts, as effects and implications of each brand can vary significantly.

REMEMBER: Pills should only be your LAST RESORT. Try to lose weight the healthy way with LIFESTYLE CHANGES, smart food choices, and EXERCISE!

Because there are many supplements and skinny pills sold over the counter that are untested for safe use, one should always exercise the utmost caution in resorting to any capsule that is marketed towards better health! Let’s discuss seven most popular weight loss solutions on the market right now.

Although this article was originally published in 2013, it was updated each year to be accurate even for 2016!

Place #1 – Phentermine (Phen375)

Phen375 product specifications

The number one on this list is called ‘Phentermine.’ Sadly, this substance requires a prescription; therefore, it has not received as high exposure as some of the other over-the-counter supplements.

There is a version called Phen375 that does not require any prescription!

It has been classified as a ‘sympathomimetic’ drug, meaning it stimulate your nervous system. The Phentermine works great for weight loss as it suppresses your appetite significantly.

Pay attention: However, you need to be aware that it can affect your heart rate and blood pressure. If you have issues with your thyroid, you should maintain extreme caution.

Phen375 Review: Is It Effective? Here’s My Answer

Click on the Image Above to Watch the Video
ATTENTION! There Is Much Safer Version of This Product That Is Among The Best Dietary Supplements for Weight Loss I Was Able to Discover – Truth About Phen375: Reviews, Ingredients, Side Effects and Much More!

Phen375 last offer image

Place #2 – D4 Thermal Shock by Cellucor

D4 Thermal Shock product specifications

The best supplement you can try for losing weight belongs to the ‘thermogenic’ category and is called D4 Thermal Shock. It works by increasing your metabolism and body’s temperature to a much higher level.

Thanks to the energy surge you will experience you will be able to burn more calories during your workout routines. Your exercises may become twice as efficient in burning calories than when you do them under the ordinary circumstances.

Pay attention: If you decide to use any thermogenic substance, you may experience tingling sensations (30-40 minutes after ingestion) or slight paranoia. You always need to begin with only a small dose instead of diving headfirst into the entire batch!

For more information and user reviews about D4 Thermal Shock check out Amazon.com

Place #3 – Xenical (120mg Orlistat)

Orlistat Xenical product specifications

Xenical (requires a prescription) was approved as a diet pill as far back as 1999, and it blocks dietary fat from being absorbed into your body. However, it reduces absorption of fat-soluble vitamins such as A, D, E, and K.

Therefore, you should not overdo the dosage when experimenting with Xenical for the very first time! You can expect to experience side-effects, such as oily stools, gas, and frequent bowel movements. All these could prove bothersome if they arose in public.

Pay attention: You should not eat a diet that is extremely rich in fatty foods. As with every other weight loss supplement, you have to ensure that you eat healthy foods at all times.

You Can Learn More About This Product on Drugs.com

Place #4 – Alli (60mg Orlistat)

Alli product specifications

The Alli is a well know brand of supplements that operates as ‘fat absorber,’ meaning it binds itself to the fat cells to make them more passable.

This enables your body to expel fatty substances quickly instead of being stored under your skin. While the fat-binding effect of Alli is notable, there are some side-effects you should be aware of including gas, cramps, and oily diarrhea.

Pay attention: All these are among side effects that can be very unpleasant and embarrassing!

You Can Learn More About This Product on Amazon.com

Place #5 – Unique Hoodia

Unique Hoodia product specifications

The Hoodia is on the fifth place on this list as instead of working on its own; this product is meant to work in tandem with the changes in your eating habits. It works by suppressing your appetite into a state that is manageable, and you will not be as susceptible to cravings and the last-minute dietary cave-ins.

Pay attention: While no objective scientific proof shows that the appetite suppressing effect is 100% efficient, there are no known side effects either, making it a safe supplement to experiment with!

You Can Learn More About This Product on BauerNutrition.com

Place #6 – Estrin D

Estrin D product specifications

One of the most popular supplements that are targeted towards menopausal women is Estrin-D. This brand is rich in caffeine and hence comes with many side-effects!

What is more, there are other ingredients present such as Vitamin B6, Magnesium, Yerba mate SE, Damiana SE, Guarana SE, Green Tea SE, Ginger and more.

Pay attention: The effects of Estrin-D are comparable to those of other caffeine-rich brands though there is no objective study to prove their actual effectiveness in weight loss.

You Can Learn More About This Product on Amazon.com

Place #7 – Green Coffee Bean Extract by Natures Design

Green Coffee Beans product specifications

The latest craze is the green coffee bean extract, which is also the most popular product trending on the fitness scene these days. It contains chlorogenic acid, which is absent from regular coffee beans due to the roasting process.

Its ability to reduce fat was tested by the University of Scranton in Pennsylvania.

Pay attention: The results showed that the participants reported a weight loss of about 10% more than those who only took the placebo. The best part? No adverse side effects were reported!

You Can Learn More About This Product on Amazon.com

Final Verdict: Try Phen375 & Lose Weight!

Phen375 last offer image

If you have struggled with weight loss in the past, or if you are just looking for something you can be sure to see results from, Phen375 is probably your best bet on the market today.

Bonus Advice: Always Look for The FDA Approval

To make sure that supplements you are going to eat are safe, you have to check whether or not it has been approved by the FDA (Food and Drug Administration). Not each and every brand on the market has passed through the examination process of this bureau!

Phentermine is an FDA-approved pill, and so should be Xenical!

Pay attention: Even once approved products should be taken with a level of caution, as they still may be scrutinized and recalled!

Hydroxycut was one of these products, which was first FDA-approved before it was studied and revealed to be directly linked to liver damage.

No matter what pill or supplement you are going to take to lose weight, it’s always wise to add a sufficient amount of exercise and healthy dietary changes. Just remember this advice – if something sounds too good to be true, STAY AWAY FROM IT!!!

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Hello, I hope you find here all the best info that will help you lose weight and feel healthy and fit!!! I want to make this site a great resource for everybody. Please always consult your decisions with your doctor. This website is for informational purposes only!!! REMEMBER: There is no such thing as a miracle cure. If something sounds too good to be true, you should be cautious. DISCLAIMER: The statements made here have not been approved by the Food and Drug Administration. These statements are not intended to diagnose, treat or cure or prevent any disease. This notice is required by the Federal Food, Drug and Cosmetic Act. Remember, I am not responsible for the comments, I am not able to verify authenticity of comments posted. Please, do your own research before you decide to take any action.
  • Susan Wilde

    Hoodia has always been my go to supplement. I have been using it for years and I’ve found it curbs my hunger like nothing else. Definitely shop around and look for a high quality product. Many contain too much filler and won’t deliver the hunger fighting properties you need to beat those pesky cravings.

    • Ashlan

      I heard there were some side effects with Hoodia. Is it addictive?

  • Stephanie

    Weight loss is a difficult concept for sure! Knowing what to do what to take and what not to take can be confusing. I know i have been confused more often than not. Trimming down your body shouldnt seem to be so hard, but it really is sometimes. I am glad I poked around long enough to find this post. I’m going to read it again to get a better idea of all the supplements you have mentioned here. Thanks for sharing.

  • Cassie

    This is a great post to be able to compare the different weight loss supplements you can find out there. I know there are tons of them but if these are the most popular of 2013 then obviously they are bound to work and you give enough information here to help people make their decision. I have seen sites where they just talk about how they help you lose weight and not really the benefits or maybe even side effects. You give all of that here and thank you.

  • Beth

    This Green Coffee Bean sounds like a winner. My life rarely allows me to fit in a full workout or even stay consistent on healthy diets, especially with having picky kids who still like their pizza and mac N cheese. Sounds like I wont need to make drastic changes in my life or eating habits and still be able to shed some pounds. I am also glad to hear about no known side effects during studies. Dont know if a busy life can handle a sick day of some sort. As far as FDA they dont approve a lot of over the counter weight loss supplements.

    • Bethany

      I remember seeing the Green Coffee Bean featured on Dr Oz a little while ago. I know that some people kind of write Dr. Oz off as being just a pop culture icon, but he actually does the research in his own lab to ensure that these products actually work before he brings them to his audience!

  • Stacey

    Ya know, I have heard and seen results from Alli, my mother and sister tried it and it seemed to work for them. I didnt try it because I thought it was another phase they were going through but I also never took the time to find out what it was about. I didnt realisze that Alli was a fat absorber. Maybe I should give it a try.

    • stella

      im 18 yr old i wnt to lose wait tel me hw many kgs cn i lose n tell me whether it hs any side effects

  • Jed

    I have been taking the green coffee beans for a few weeks now and they do seem to be helping although i have a long way to go. I haven’t had any negative side effects too which i have experienced with other weight loss pills.

  • Jed

    I was thinking about taking Phentermine but i think i will give it a miss after reading that it affects your nervous system

    • Lucy

      Yeah, I don’t think any diet is worth nerve damage. Then what would be the fun in being thin?

    • saz

      I think its phen375 people r talking about. its safe

  • Madeline

    I have tried all different methods of loosing weight but non of them have seemed to work very effectively for the amount of effort put in. Im hoping to try some of these weight loss pills (not all at the same time don’t worry) and see which ones work best for me.

  • Micheal

    Id definitely take advice of the FDA approval, otherwise you don’t know what you are putting inside your body and it could be alot worse than fatty foods.

  • Leanne

    Ive alway said pills arent the answer but the alli has worked really well for me in the past.

    • Mariah G

      A lot of people like Alli so I’m told. My friends have been using it. I’ve seen the book, but never taken the pills. The book has a lot of diet guides and meal plans in it. They seem pretty healthy all by themselves. Does the pill really help?

  • Charlotte

    Isnt the d4 dangerous? I thought if your raise or lower your resting body core temperature by only a small amount you could be in for problems? or have i mis understood this

  • Louise

    I have started the slimming green coffee beans recently and have started to notice the difference already. Unlike the guys in the study i have cut back a little on fatty foods but they seem to be working really well in line with a healthier (not totally healthy) diet.

  • Michelle

    10 percent fat loss in 22 weeks is fantastic, I may just have to try the green coffee bean slimming pills.

  • Stacey.

    I have tried the Allii pills and can assure you they work great but the side effects are too much for me. I have had to stop taking them and now i am looking for alternatives.

  • Jennifer

    I am always wary about taking pills, i have heard a ton of horror stories over the years regarding slimming pills. Thank you for this informative article.

  • Shirly

    Not to big on workouts, but I do a lot of physical work on a ranch and I

    think the D4 Thermal Shock would be a great supplement for me at any time

    of the year. Just wondering if I will be hotter in the summer though.

    Well I guess it’s better to be hot than fat. Will make sure to start out

    small too. Thanks for that warning

    • Raymond

      I know you may not be too big on workouts Shirly, but I also have a very physically intense job, and found that my energy level totally skyrocketed when I took a few hours a week to workout, even on top of it all. It’s a different type of work, working versus working out.

  • Linda

    I’ve heard a lot of talk lately about Green Coffee Bean extract and how effective it is. I’m very curious about this product and I really appreciate that you’ve taken the time to report on how it works and how it differs from normal roasted coffee. I can see myself trying this product in the future.

  • Jess MN

    I’ve been working so hard to lose weight this year. I’ve seen real results through diet and exercise but I’ve hit a plateau and everyday is a struggle. I’m not seeing results anymore and it is so hard to stay motivated. I’m considering adding a supplement to my regimen. I’ve heard good things about Alli and Hoodia but some of the others you’ve listed here sound amazing. I’ll be reading up on them. Thank you for the information!

  • Sioux

    All of my friends have been raving about these Green Coffee Beans, but this is the first article I’ve seen that actually talks about how they really work. It’s interesting, maybe I will give them a try. Are there any foods that are naturally high in cholinergic acid that I might just try adding to my diet. or are the supplements really that much more effective?

  • http://kinkytails.blogspot.com/ Lindsay Niles

    Green Coffee bean extract sounds like a supplement that’s worth researching. I’m not familiar with the benefits of chlorogenic acid as a fat burner but the trial seems to suggest that it is very effective. Paired with diet and exercise I could see this being a very powerful aid.

    I’ll be on the lookout for more information about this supplement.

  • Jessica K. Parker

    With so many pills and programs on the market it can be difficult to know you’re choosing the right one. That’s why it’s so important to thoroughly research your options. Read reviews, ask questions and don’t make rash decisions until you’re certain you’ve covered all your bases. Supplements and other weight loss aids can be very helpful but you need to be well-informed.

  • Mina Mathews

    I don’t know which supplement would best suit my needs. I have a slow metabolism. I do exercise and I watch what I eat but I sometimes struggle with overeating. I want a natural weight loss aid that is safe and won’t leave me feeling jittery, bloated or nauseous. Any suggestions?

  • Mark

    It’s true that one should always approach weight loss aids with a certain level of caution but that isn’t to say that some are not truly safe and beneficial. You’ve composed a very good list showing the pros and cons of some of the most well-known and effective supplements. This is exactly the sort of information one needs in order to make an informed decision.

  • Holly

    I prefer the more natural supplements because they seem to be the safest and their side effects are mild.

    I’ve tried Hoodia and found it helped me curb my hunger. I’ve also been seeing a lot of talk about Green Coffee Beans lately but I have yet to try the supplement, though I am curious.

  • L. Slattery

    I’ve been thinking about trying Alli. There’s so many positive reviews for it and I’ve heard that the possible side effects are really not as bad or as common as some people make them out to be. If you’re eating a low fat diet to begin with it is unlikely you’ll experience bad gas or messy bowel movements. Maybe that would happen if you’re loading up on greasy snacks and fast food but I really have to question why anyone would if they’re actively trying to lose weight.

    I think a lot of the potential side effects on the fat blocking supplements are overblown.

  • Allen Rogers

    I tried Hoodia but it didn’t work for me. It didn’t diminish my hunger at all, which I thought was weird because many of my friends said it worked for them.

    I later found out that you need to be careful when buying it because many brands don’t have enough of the active ingredient in the pills to make any difference. Do your research and make sure you’re buying a quality supplement.

  • Lynn Ross

    Thank you for this list! I’m in the process of looking for a good weight loss supplement and I really appreciate that you’ve taken the time to review the best ones.

    I’m intrigued by the Green Coffee Beans supplement. It seems very effective and I like that there are no known side effects.

  • Amanda Austin

    I have always been skeptical about diet pills, and honestly a little scared to take them because I have heard so many horror stories, but your list is very informative and put a lot of my concerns to rest. I am especially interested in Green Coffee Beans, I think I am going to give them a shot. Thanks for the information!

    • MyMeratolReview.com

      So, if you take the Green Coffee Beans, do you intend to take them on an ongoing basis or just for a time?

  • Grace

    Interesting list of supplements. Alli is the only one I am familiar with out of the group. I have heard of Hoodia and other saying they have had positive results from using it.Out of the list I am finding the green coffee bean supplement to be interesting. I think I would like to give it a try it might be promising.

  • http://beloveddolldesigns.com/ BD

    “On a similar note, if one does not exercise caution in monitoring exactly what goes into a supplement that they take, then they may very well find that the repercussions actually outweigh the benefits.” – worth repeating.

    Our society is basically a pill-popper. What many people don’t realize is that yeah, sure the med might help with one symptom you have, but it can cause two more to pop up so then you have to take capsules for those. Look at any diabetic or senior citizen’s repertoire of meds. It is insane how much they have to take!